Sleep Schedule Disruption and Circadian Misalignment: Health Effects, Mechanisms, and Protective Strategies
Sleep schedule disruption and circadian misalignment occur when daily sleep–wake timing does not match the body’s internal biological clock, primarily regulated by the suprachiasmatic nucleus (SCN) in the hypothalamus. This mismatch is common during travel, shift work, and extended periods of altered routines. When an individual repeatedly attempts to function and sleep at times that… Read More »