Tebentafusp (Kimmtrak) and TCR-based Immunotherapy in Metastatic Ocular Melanoma: Mechanisms and Clinical Promise
Metastatic ocular melanoma (OM) is a rare but potentially lethal malignancy arising from melanocytes in the uveal tract (choroid, ciliary body, or iris). Compared with cutaneous melanoma, ocular melanoma has distinct biology and clinical behavior, including a high propensity for hematogenous spread, particularly to the liver. Traditional systemic cytotoxic chemotherapy has historically yielded limited durability,… Read More »