Cancer Research and Translational Oncology: From Molecular Mechanisms to Patient-Focused Therapies and Outcomes
Cancer is a broad family of diseases characterized by uncontrolled cellular proliferation, invasion, and the ability to metastasize. At the molecular level, malignancy arises when genomic alterations disrupt normal cell-cycle control, apoptosis, DNA repair, and differentiation pathways. Common driver events include activating mutations in oncogenes (promoting growth signals), inactivating tumor suppressor genes (removing growth restraints),… Read More »