Seasonal Allergic Rhinitis: Why Local Honey Does Not Work as Immunotherapy for Pollen Sensitization
Seasonal allergic rhinitis (SAR) is an IgE-mediated hypersensitivity disorder driven by inhaled environmental allergens, most commonly pollens from wind-pollinated grasses, trees, and weeds. In susceptible individuals, repeated exposure to specific allergenic pollen proteins triggers a cascade beginning with allergen presentation by airway antigen-presenting cells. This promotes allergen-specific T-helper type 2 (Th2) polarization, leading to B-cell… Read More »