

Developing: Christina Applegate says doctors have determined she does not have multiple sclerosis after all, revising a diagnosis she had publicly discussed for years, according to reporting from KSL.com and other outlets citing her remarks on the podcast she co-hosts with actress Jamie Lynn Sigler.
In the KSL.com report published Thursday, Applegate said recent testing showed she does not have MS, leaving her “back at square one” as doctors continue trying to determine what is causing her symptoms. Vox also reported that Applegate made the revelation on Sigler’s podcast, MeSsy, saying she still does not have a confirmed explanation for her ongoing health problems.
Applegate had previously said she was diagnosed with multiple sclerosis in 2021 and later became one of the disease’s most visible public advocates. According to the reporting, the latest tests prompted doctors to reconsider that diagnosis, but neither Applegate nor the outlets identified a new condition in the materials reviewed.
The exact cause of her symptoms remains unknown, and there is no indication in the supplied reporting that a final diagnosis has been announced. This remains a developing health story.


