By Trend News Line 2024-05-23 00:00:00.
**Teen with Relapsed Leukemia Develops Rare Fungal Infection**
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A young 18-year-old girl, who had been battling high-risk acute myeloid leukemia (AML), faced a new and unexpected challenge in her medical journey. After undergoing treatment and experiencing a relapse of her AML, she developed cellulitis in her gluteal region, followed by alarming skin lesions on her left hip and buttocks.
**Initial Diagnosis and Treatment**
The teenager was first diagnosed with high-risk AML in May 2021 and completed treatment under the Children’s Oncology Group study protocol AAML0531 in December of the same year. Unfortunately, in April 2022, she experienced a relapse of her AML and underwent a cycle of relapse therapy with various medications.
**Complications and Hospitalization**
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Soon after her relapse treatment, the patient developed cellulitis in her gluteal region, which required hospitalization. She was treated with antibiotics but later developed new skin lesions on her left hip and buttocks, which raised concerns among her medical team.
**Unusual Skin Lesions**
The skin lesions on the patient’s left hip started as red spots and quickly progressed to swollen, blackened areas. Additional lesions appeared on her buttocks, resembling boils. Despite being on antibiotics and antifungal medication, the lesions continued to worsen, prompting further investigation.
**Discovery of Rare Fungal Infection**
Upon admission, the patient’s skin lesions were initially thought to be caused by bacterial infections. However, a biopsy revealed the presence of aseptate hyphae, indicating a fungal infection. Further testing identified the organism as Lagenidium deciduum, a rare and challenging fungal pathogen.
**Treatment and Recovery**
The patient underwent surgical excision of the infected areas and began treatment with a tailored antifungal regimen. Despite initial challenges with identifying an effective treatment, the medical team successfully managed the fungal infection. The patient was discharged home with ongoing antifungal therapy and enrolled in a clinical trial for a stem cell transplant to address her AML.
**Positive Outcome**
Following her stem cell transplant, the patient remained free of fungal disease and experienced a successful recovery. Her full clinical course, including the challenges she faced and the treatments she received, highlighted the resilience and determination of this young individual in her fight against cancer and a rare fungal infection.
**Conclusion**
The story of this young girl’s battle with leukemia and a rare fungal infection serves as a reminder of the complexities and uncertainties in medical treatment. Through the dedication of her medical team and her own strength, she overcame significant challenges and emerged victorious in her fight for health and well-being..
Cutaneous Lagenidium deciduum infection
Acute myeloid leukemia.
