By Trend News Line 2024-03-19 15:32:47.
In a groundbreaking study published in JAMA Network Open, researchers in France have compared the effectiveness of ketamine and morphine for out-of-hospital analgesia in patients with traumatic pain. The study, led by Le Cornec C and team, involved 251 patients over the age of 18 who presented with severe acute traumatic pain to 11 emergency medical services in France.
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**The Trial Details**
The patients were randomly assigned to either the intervention group or the comparator group. The intervention group received ketamine, while the comparator group received morphine. The primary outcome measured was the change in verbal numeric pain scale 30 minutes after treatment.
**Results**
The study found that both ketamine and morphine were effective in reducing pain, with similar reductions in pain scores observed in both groups. However, adverse events were more common in the ketamine group, with emergence phenomenon being the most common side effect.
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**Discussion**
The study sheds light on the potential of ketamine as an alternative to opioids for managing pain, especially in the prehospital setting. While ketamine showed promising results in terms of pain reduction, its higher incidence of adverse events raises concerns about its widespread use.
**Implications**
The findings of this study have important implications for prehospital pain management. Ketamine could be a viable option for patients with traumatic pain, particularly for those who may be at risk of opioid dependency. However, further research is needed to fully understand the implications of using ketamine as an analgesic in the prehospital setting.
**Conclusion**
In conclusion, the study by Le Cornec C et al. provides valuable insights into the use of ketamine compared to morphine for out-of-hospital analgesia in patients with traumatic pain. While ketamine shows promise as an alternative to opioids, its side effect profile warrants further investigation. This research opens up new possibilities for pain management strategies and highlights the importance of exploring non-opioid alternatives in the field of emergency medicine..
1. Ketamorph differences
2. Ketamine vs morphine effects.
